
Professor In Residence
M_MED-ZSFG-PULM
+1 415 476-0735
I have a particular interest in clinical management of multidrug resistant tuberculosis (MDR-TB) in high HIV burden settings in Southern Africa. My research includes the development of non-invasive pharmacokinetic measures to enhance MDR-TB drug development and clinical trials. I am a member of the AIDS Clinical Trials Group TB Transformative Science Group, and have specialized training in epidemiology, statistical prediction, and diagnostic test evaluation. I am a specialty editor for respiratory diseases at PLoS Medicine.
Publications
Frequency, kinetics and determinants of viable SARS-CoV-2 in bioaerosols from ambulatory COVID-19 patients infected with the Beta, Delta or Omicron variants.
Frontiers in medicine
Health care seeking patterns of rifampicin-resistant tuberculosis patients in Harare, Zimbabwe: A prospective cohort study.
Research Square
Xpert MTB/RIF-detected Rifampicin Resistance is a Sub-Optimal Surrogate for Multidrug Resistant Tuberculosis in Eastern Democratic Republic of the Congo: Diagnostic and Clinical Implications.
The American journal of tropical medicine and hygiene
Validated LC-MS/MS Panel for Quantifying 11 Drug-Resistant TB Medications in Small Hair Samples.
Clinical trials (London, England)
Correlation of Linezolid Hair Concentrations with Plasma Exposure in Patients with Drug-Resistant Tuberculosis.
AIDS patient care and STDs
Chronic lung disease in adult recurrent tuberculosis survivors in Zimbabwe: a cohort study.
JCI insight
Mycobacterium tuberculosis Subculture Results in Loss of Potentially Clinically Relevant Heteroresistance.
AIDS patient care and STDs
Chronic lung disease in HIV-infected children established on antiretroviral therapy.
The Lancet regional health. Southeast Asia
Tuberculosis progression rates in U.S. Immigrants following screening with interferon-gamma release assays.
PLOS global public health
Serial testing for latent tuberculosis using QuantiFERON-TB Gold In-Tube: A Markov model.
The Lancet. Microbe
A multi-analyte panel for non-invasive pharmacokinetic monitoring of second-line anti-tuberculosis drugs.
JCI insight
Xpert(®) MTB/RIF detection of rifampin resistance and time to treatment initiation in Harare, Zimbabwe.
JCI insight
Re-inventing adherence: toward a patient-centered model of care for drug-resistant tuberculosis and HIV.
JCI insight
Moving Beyond Directly Observed Therapy for Tuberculosis.
M_MED-ZSFG-AIDS
Genomic epidemiology of multidrug-resistant Mycobacterium tuberculosis during transcontinental spread.
The Journal of antimicrobial chemotherapy
Analysis of Green Light Committee implementation and acquisition of second-line drug resistance.
The American journal of tropical medicine and hygiene
Empiric tuberculosis treatment in retreatment patients in high HIV/tuberculosis-burden settings.
Essential Strategies for Leveraging AI in the Global HIV Response
Drug-resistant tuberculosis in high-risk groups, Zimbabwe.
Journal of general internal medicine
Rapid molecular testing for TB to guide respiratory isolation in the U.S.: a cost-benefit analysis.
Research Square
Rifampin monoresistant tuberculosis and HIV comorbidity in California, 1993-2008: a retrospective cohort study.
The Lancet regional health. Southeast Asia
A transcriptional signature for active TB: have we found the needle in the haystack?
M_MED-ZSFG-AIDS
Tuberculosis and HIV co-infection, California, USA, 1993–2008.
Journal of general internal medicine
Microscopic-observation drug-susceptibility assay for the diagnosis of drug-resistant tuberculosis in Harare, Zimbabwe.
Research Square
Impact of isoniazid resistance-conferring mutations on the clinical presentation of isoniazid monoresistant tuberculosis.
Research Square
Interferon-? release assays for active pulmonary tuberculosis diagnosis in adults in low- and middle-income countries: systematic review and meta-analysis.
The Journal of antimicrobial chemotherapy
TB/HIV: an orphan disease?
member
Determinants of multidrug-resistant tuberculosis clusters, California, USA, 2004-2007.
Journal of general internal medicine
Clinical characteristics and treatment outcomes of patients with isoniazid-monoresistant tuberculosis.
The American journal of tropical medicine and hygiene
Leptospirosis-associated severe pulmonary hemorrhagic syndrome, Salvador, Brazil.
Journal of general internal medicine