
Professor In Residence
M_MED-ZSFG-PULM
+1 415 476-0735
I have a particular interest in clinical management of multidrug resistant tuberculosis (MDR-TB) in high HIV burden settings in Southern Africa. My research includes the development of non-invasive pharmacokinetic measures to enhance MDR-TB drug development and clinical trials. I am a member of the AIDS Clinical Trials Group TB Transformative Science Group, and have specialized training in epidemiology, statistical prediction, and diagnostic test evaluation. I am a specialty editor for respiratory diseases at PLoS Medicine.
Publications
Health care seeking patterns of rifampicin-resistant tuberculosis patients in Harare, Zimbabwe: A prospective cohort study.
Research Square
Xpert MTB/RIF-detected Rifampicin Resistance is a Sub-Optimal Surrogate for Multidrug Resistant Tuberculosis in Eastern Democratic Republic of the Congo: Diagnostic and Clinical Implications.
The American journal of tropical medicine and hygiene
Chronic lung disease in adult recurrent tuberculosis survivors in Zimbabwe: a cohort study.
JCI insight
Tuberculosis progression rates in U.S. Immigrants following screening with interferon-gamma release assays.
PLOS global public health
A multi-analyte panel for non-invasive pharmacokinetic monitoring of second-line anti-tuberculosis drugs.
JCI insight
Xpert(®) MTB/RIF detection of rifampin resistance and time to treatment initiation in Harare, Zimbabwe.
JCI insight
Re-inventing adherence: toward a patient-centered model of care for drug-resistant tuberculosis and HIV.
JCI insight
Moving Beyond Directly Observed Therapy for Tuberculosis.
M_MED-ZSFG-AIDS
Genomic epidemiology of multidrug-resistant Mycobacterium tuberculosis during transcontinental spread.
The Journal of antimicrobial chemotherapy
Analysis of Green Light Committee implementation and acquisition of second-line drug resistance.
The American journal of tropical medicine and hygiene
Rapid molecular testing for TB to guide respiratory isolation in the U.S.: a cost-benefit analysis.
Research Square
A transcriptional signature for active TB: have we found the needle in the haystack?
M_MED-ZSFG-AIDS
Microscopic-observation drug-susceptibility assay for the diagnosis of drug-resistant tuberculosis in Harare, Zimbabwe.
Research Square
Impact of isoniazid resistance-conferring mutations on the clinical presentation of isoniazid monoresistant tuberculosis.
Research Square
Interferon-? release assays for active pulmonary tuberculosis diagnosis in adults in low- and middle-income countries: systematic review and meta-analysis.
The Journal of antimicrobial chemotherapy
TB/HIV: an orphan disease?
member
Clinical characteristics and treatment outcomes of patients with isoniazid-monoresistant tuberculosis.
The American journal of tropical medicine and hygiene