Professor of Clinical Medicine
M_MED-ZSFG-AIDS
I specialize in HIV/AIDS and have clinical responsibilities including outpatient services at the San Francisco General Hospital HIV clinic as well as inpatient services on the HIV/AIDS, general medicine, and infectious diseases consult services. I direct the HIV Clinical Trials Group at SFGH, which conducts investigator-initiated and industry HIV trials. I am site investigator for the Adult AIDS Clinical Trials Group (ACTG), and my research interests include HIV and TB coinfection, development of novel TB diagnostics, and HIV and viral hepatitis coinfection.
Publications
Doxycycline Resistance and 16S rRNA Mutations in Treponema pallidum.
Emerging infectious diseases
Acceptability and use of doxyPEP among cisgender men who have sex with men, transgender women and non-binary persons assigned male sex at birth: results from a national online survey from the USA.
Sexually transmitted infections
The Last Mile: Understanding Barriers to Hepatitis C Virus Microelimination Among People with HIV in San Francisco, 2021-2024.
Open forum infectious diseases
Temporal Trends in Hepatitis C Virus Screening and Management in Pregnant Women and Infants Between 2014 and 2024 in San Francisco, California.
The American journal of gastroenterology
Assessment of RNA at SVR4 and Treatment Completion as Alternative Measures of Hepatitis C Cure for People Who Inject Drugs.
Open forum infectious diseases
Doxy-PEP could select for ceftriaxone resistance in Neisseria gonorrhoeae - Authors' reply.
The Lancet. Infectious diseases
Doxycycline to prevent bacterial sexually transmitted infections in the USA: final results from the DoxyPEP multicentre, open-label, randomised controlled trial and open-label extension.
The Lancet. Infectious diseases
Long-term in vitro exposure of Treponema pallidum to sub-bactericidal doxycycline did not induce resistance: Implications for doxy-PEP and syphilis.
The Journal of antimicrobial chemotherapy
Facilitating access to direct-acting antivirals in a community-based point-of-diagnosis model for hepatitis C treatment: The role of the pharmacy team in the no one waits (NOW) study.
The International journal on drug policy
Evaluating Demographic Representation in Clinical Trials: Use of the Adaptive Coronavirus Disease 2019 Treatment Trial (ACTT) as a Test Case.
Gates open research
Remdesivir for the Treatment of Covid-19 - Preliminary Report.
M_MED-CORE-PULM
Ledipasvir/Sofosbuvir for 8 Weeks to Treat Acute Hepatitis C Virus Infections in Men With Human Immunodeficiency Virus Infections: Sofosbuvir-Containing Regimens Without Interferon for Treatment of Acute HCV in HIV-1 Infected Individuals.
The American journal of tropical medicine and hygiene
A pilot metabolomics study of tuberculosis immune reconstitution inflammatory syndrome.
Frontiers in reproductive health
Localized US Efforts to Eliminate Hepatitis C.
Journal of surgical education
Grazoprevir, ruzasvir, and uprifosbuvir for hepatitis C virus after NS5A treatment failure.
Toxicological sciences : an official journal of the Society of Toxicology
Disabling Dactylitis and Tenosynovitis Due to Mycobacterium haemophilum in a Patient With Human Immunodeficiency Virus/Acquired Immune Deficiency Syndrome.
Gates open research
Sofosbuvir and Velpatasvir for the Treatment of Hepatitis C Virus in Patients Coinfected With Human Immunodeficiency Virus Type 1: An Open-Label, Phase 3 Study.
The American journal of tropical medicine and hygiene
Understanding Hepatitis C Virus Drug Resistance: Clinical Implications for Current and Future Regimens.
Cancer discovery
Elbasvir-Grazoprevir to Treat Hepatitis C Virus Infection in Persons Receiving Opioid Agonist Therapy: A Randomized Trial.
American journal of medical genetics
A survey of tuberculosis infection control practices at the NIH/NIAID/DAIDS-supported clinical trial sites in low and middle income countries.
H-Center for TB
CROI 2016: Viral Hepatitis and Liver Fibrosis.
Cancer discovery
12 Weeks of Daclatasvir in Combination With Sofosbuvir for HIV-HCV Coinfection (ALLY-2 Study): Efficacy and Safety by HIV Combination Antiretroviral Regimens.
The American journal of tropical medicine and hygiene
Evaluation of Xpert MTB/RIF Versus AFB Smear and Culture to Identify Pulmonary Tuberculosis in Patients With Suspected Tuberculosis From Low and Higher Prevalence Settings.
The American journal of tropical medicine and hygiene
CROI 2015: Highlights of Viral Hepatitis Therapy.
Cancer discovery
Combined effect of CYP2B6 and NAT2 genotype on plasma efavirenz exposure during rifampin-based antituberculosis therapy in the STRIDE study.
The American journal of tropical medicine and hygiene
Phase I safety, pharmacokinetics, and pharmacogenetics study of the antituberculosis drug PA-824 with concomitant lopinavir-ritonavir, efavirenz, or rifampin.
AIDS patient care and STDs
CROI 2014: Viral hepatitis and complications of HIV disease and antiretroviral therapy.
Cancer discovery
HIV-associated central nervous system tuberculosis.
CPT: pharmacometrics & systems pharmacology
Tuberculosis immune reconstitution inflammatory syndrome in A5221 STRIDE: timing, severity, and implications for HIV-TB programs.
PLoS pathogens
Addition of nitazoxanide to PEG-IFN and ribavirin to improve HCV treatment response in HIV-1 and HCV genotype 1 coinfected persons naïve to HCV therapy: results of the ACTG A5269 trial.
The Journal of infection
Relationship between weight, efavirenz exposure, and virologic suppression in HIV-infected patients on rifampin-based tuberculosis treatment in the AIDS Clinical Trials Group A5221 STRIDE Study.
The American journal of tropical medicine and hygiene
CROI 2013: Complications of HIV disease, viral hepatitis, and antiretroviral therapy.
Cancer discovery
Complications of HIV disease and antiretroviral therapy.
Cancer discovery
Resistance patterns and response to entecavir intensification among HIV-HBV-coinfected adults with persistent HBV viremia.
PLoS pathogens
Complications of HIV disease and antiretroviral therapy.
Cancer discovery
Current issues in the diagnosis and management of tuberculosis and HIV coinfection in the United States.
Medical decision making : an international journal of the Society for Medical Decision Making
Significant variation in presentation of pulmonary tuberculosis across a high resolution of CD4 strata.
JCI insight
Tuberculosis as part of the natural history of HIV infection in developing countries.
The American journal of tropical medicine and hygiene
Complications of HIV disease and antiretroviral treatment.
Medical decision making : an international journal of the Society for Medical Decision Making
Antiretroviral therapy and TB.
Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation
Person Type Override (full)