Devan Jaganath, MD, MPH

UCSF Center for Tuberculosis Pediatric TB Chair
Assistant Professor
Pediatrics
+1 415 514-4692

My research is focused on diagnostics, biomarker discovery, data science and digital health to improve TB care, with a particular interest in childhood TB. I am part of the END Childhood TB Study in Kampala, Uganda to evaluate novel non-sputum, biomarker-based tests for pediatric intra-thoracic TB. In biomarker discovery, I am working to identify a urine-based proteomic biosignature for diagnosing childhood TB, and I am part of the COMBO study to examine other novel pathogen and host biomarkers for TB diagnosis in children. I also examine mobile and digital health innovations to improve TB diagnosis and monitoring, including the development of electronic medical record (EMR)-based tools to improve the screening and management of children with latent TB infection.

UCSF Center for Tuberculosis Leadership & Initiatives:
Chair/Lead, UCSF CTB Maternal and Childhood TB Initiative
SMART4TB UCSF Lead, Operational Research
TB RAMP Scholar | Class 2023
BATS Planning Committee 2023
World TB Day Planning Committee 2022-23
BATS Rising Star 2022

Publications: 

Solicited Cough Sound Analysis for Tuberculosis Triage Testing: The CODA TB DREAM Challenge Dataset.

medRxiv : the preprint server for health sciences

Huddart S, Yadav V, Sieberts SK, Omberg L, Raberahona M, Rakotoarivelo R, Lyimo IN, Lweno O, Christopher DJ, Nhung NV, Theron G, Worodria W, Yu CY, Bachman CM, Burkot S, Dewan P, Kulhare S, Small PM, Cattamanchi A, Jaganath D, Lapierre SG

Epidemiology and Treatment Outcomes of Tuberculosis with Chronic Hepatitis B Infection-California, 2016-2020.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Bertumen JB, Pascopella L, Han E, Glenn-Finer R, Wong RJ, Chitnis A, Jaganath D, Jewell M, Gounder P, McElroy S, Stockman L, Barry P

The socioeconomic burden of pediatric tuberculosis and role of child-sensitive social protection.

BMC public health

Shah K, Nakafeero J, Kadota JL, Wambi P, Nanyonga G, Kiconco E, Deus A, Sekadde MP, Nabukenya-Mudiope MG, Tukamuhebwa HA, Mupere E, Mohanty S, Cattamanchi A, Wobudeya E, Shete PB, Jaganath D

Predicting pediatric TB: the need for age-specific host biosignatures.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Suliman S, Jaganath D, DiNardo A

Clinical standards for drug-susceptible TB in children and adolescents.

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease

Chiang SS, Graham SM, Schaaf HS, Marais BJ, Sant'Anna CC, Sharma S, Starke JR, Triasih R, Achar J, Amanullah F, Armitage LY, Aurilio RB, Buck WC, Centis R, Chabala C, Cruz AT, Demers AM, du Preez K, Enimil A, Furin J, Garcia-Prats AJ, Gonzalez NE, Hoddinott G, Isaakidis P, Jaganath D, Kabra SK, Kampmann B, Kay A, Kitai I, Lopez-Varela E, Maleche-Obimbo E, Malaspina FM, Velásquez JN, Nuttall JJC, Oliwa JN, Andrade IO, Perez-Velez CM, Rabie H, Seddon JA, Sekadde MP, Shen A, Skrahina A, Soriano-Arandes A, Steenhoff AP, Tebruegge M, Tovar MA, Tsogt B, van der Zalm MM, Welch H, Migliori GB

Epidemiology of Culture-Negative Pulmonary Tuberculosis-Alameda County, 2010-2019.

Journal of public health management and practice : JPHMP

Chen J, Marusinec R, Brown R, Shiau R, Jaganath D, Chitnis AS

Continuous cough monitoring: a novel digital biomarker for TB diagnosis and treatment response monitoring.

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease

Huddart S, Asege L, Jaganath D, Golla M, Dang H, Lovelina L, Derendinger B, Andama A, Christopher DJ, Nhung NV, Theron G, Denkinger CM, Nahid P, Cattamanchi A, Yu C

Social Determinants of Adherence to Treatment for Tuberculosis Infection and Disease Among Children, Adolescents, and Young Adults: A Narrative Review.

Journal of the Pediatric Infectious Diseases Society

Leddy AM, Jaganath D, Triasih R, Wobudeya E, Bellotti de Oliveira MC, Sheremeta Y, Becerra MC, Chiang SS

Tuberculosis Disease Among Adults Aged 65 Years and Older: Alameda County, California, 2016-2019.

Open forum infectious diseases

Wu IL, Chen J, Shiau R, Chitnis AS, Jaganath D

The Role of C-Reactive Protein as a Triage Tool for Pulmonary Tuberculosis in Children.

Journal of the Pediatric Infectious Diseases Society

Jaganath D, Reza TF, Wambi P, Nakafeero J, Kiconco E, Nanyonga G, Oumo EA, Nsereko MC, Sekadde MP, Nabukenya-Mudiope MG, Kato-Maeda M, Andama A, Yoon C, Mohanty S, Wobudeya E, Cattamanchi A

Making cough count in tuberculosis care.

Communications medicine

Zimmer AJ, Ugarte-Gil C, Pathri R, Dewan P, Jaganath D, Cattamanchi A, Pai M, Grandjean Lapierre S

Accuracy of Tongue Swab Testing Using Xpert MTB-RIF Ultra for Tuberculosis Diagnosis.

Journal of clinical microbiology

Andama A, Whitman GR, Crowder R, Reza TF, Jaganath D, Mulondo J, Nalugwa TK, Semitala FC, Worodria W, Cook C, Wood RC, Weigel KM, Olson AM, Lohmiller Shaw J, Kato-Maeda M, Denkinger CM, Nahid P, Cangelosi GA, Cattamanchi A

A narrative review of tuberculosis in the United States among persons aged 65 years and older.

Journal of Clinical Tuberculosis and Other Mycobacterial Diseases

Wu IL, Chitnis AS, Jaganath D

Tuberculosis in Children.

Infectious disease clinics of North America

Jaganath D, Beaudry J, Salazar-Austin N

Engineered Electroactive Solutions for Electrochemical Detection of Tuberculosis-Associated Volatile Organic Biomarkers.

IEEE Sensors Journal

Willis CN, Larson SR, Andama A, Jaganath D, Misra M, Cattamanchi A, Mohanty SK

Diagnosis and Treatment of Latent Tuberculosis Infection.

The American journal of gastroenterology

Chitnis AS, Jaganath D, Gish RG, Wong RJ

Author Correction: Lipoarabinomannan antigenic epitope differences in tuberculosis disease subtypes.

Scientific reports

Magni R, Rruga F, Alsaab FM, Sharif S, Howard M, Espina V, Kim B, Lepene B, Lee G, Alayouni MA, Steinberg H, Araujo R, Kashanchi F, Riccardi F, Morreira S, Araujo A, Poli F, Jaganath D, Semitala FC, Worodria W, Andama A, Choudhary A, Honnen WJ, Petricoin EF, Cattamanchi A, Colombatti R, de Waard JH, Oberhelman R, Pinter A, Gilman RH, Liotta LA, Luchini A

Toward Comprehensive Plasma Proteomics by Orthogonal Protease Digestion.

Journal of proteome research

Fossati A, Richards AL, Chen KH, Jaganath D, Cattamanchi A, Ernst JD, Swaney DL

A Prospective Evaluation of Xpert MTB/RIF Ultra for Childhood Pulmonary Tuberculosis in Uganda.

Journal of the Pediatric Infectious Diseases Society

Jaganath D, Wambi P, Reza TF, Nakafeero J, Aben EO, Kiconco E, Nannyonga G, Nsereko M, Sekadde MP, Mudiope M, Kato-Maeda M, Starke J, Andama A, Mohanty S, Wobudeya E, Cattamanchi A

The transition to Xpert MTB/RIF ultra: diagnostic accuracy for pulmonary tuberculosis in Kampala, Uganda.

BMC infectious diseases

Andama A, Jaganath D, Crowder R, Asege L, Nakaye M, Katumba D, Mukwatamundu J, Mwebe S, Semitala CF, Worodria W, Joloba M, Mohanty S, Somoskovi A, Cattamanchi A

Lipoarabinomannan antigenic epitope differences in tuberculosis disease subtypes.

Scientific reports

Magni R, Rruga F, Alsaab F, Sharif S, Howard M, Espina V, Kim B, Lepene B, Lee G, Alayouni MA, Steinberg H, Araujo R, Kashanchi F, Riccardi F, Morreira S, Araujo A, Poli F, Jaganath D, Semitala FC, Worodria W, Andama A, Choudhary A, Honnen WJ, Petricoin EF, Cattamanchi A, Colombatti R, de Waard JH, Oberhelman R, Pinter A, Gilman RH, Liotta LA, Luchini A

Evaluation of multi-antigen serological screening for active tuberculosis among people living with HIV.

PloS one

Jaganath D, Rajan J, Yoon C, Ravindran R, Andama A, Asege L, Mwebe SZ, Katende J, Nakaye M, Semitala FC, Khan IH, Cattamanchi A

Accuracy and incremental yield of urine Xpert MTB/RIF Ultra versus Determine TB-LAM for diagnosis of pulmonary tuberculosis.

Diagnostic microbiology and infectious disease

Andama A, Jaganath D, Crowder R, Asege L, Nakaye M, Katumba D, Mwebe S, Semitala F, Worodria W, Joloba M, Mohanty S, Somoskovi A, Cattamanchi A

Outcomes of empiric treatment for pediatric tuberculosis, Kampala, Uganda, 2010-2015.

BMC public health

Wobudeya E, Jaganath D, Sekadde MP, Nsangi B, Haq H, Cattamanchi A

Seasonality of childhood tuberculosis cases in Kampala, Uganda, 2010-2015.

PloS one

Jaganath D, Wobudeya E, Sekadde MP, Nsangi B, Haq H, Cattamanchi A

Desirability of Clinic-Based Financial Services in Urban Pediatric Primary Care.

The Journal of pediatrics

Jaganath D, Johnson K, Tschudy MM, Topel K, Stackhouse B, Solomon BS

"In the Clinic They Know Us": Preferences for Clinic-Based Financial and Employment Services in Urban Pediatric Primary Care.

Academic pediatrics

Quinn C, Johnson K, Raney C, Baker J, Topel K, Tschudy MM, Jaganath D, Solomon BS

Staphylococcus aureus Bacteremia Incidence and Methicillin Resistance in Rural Thailand, 2006-2014.

The American journal of tropical medicine and hygiene

Jaganath D, Jorakate P, Makprasert S, Sangwichian O, Akarachotpong T, Thamthitiwat S, Khemla S, DeFries T, Baggett HC, Whistler T, Gregory CJ, Rhodes J

Revisiting the mutant prevention concentration to guide dosing in childhood tuberculosis.

The Journal of antimicrobial chemotherapy

Jaganath D, Schaaf HS, Donald PR

Carbapenems against Mycobacterium tuberculosis: a review of the evidence.

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease

Jaganath D, Lamichhane G, Shah M

Modelling subject-specific childhood growth using linear mixed-effect models with cubic regression splines.

Emerging themes in epidemiology

Grajeda LM, Ivanescu A, Saito M, Crainiceanu C, Jaganath D, Gilman RH, Crabtree JE, Kelleher D, Cabrera L, Cama V, Checkley W

Urbanisation but not biomass fuel smoke exposure is associated with asthma prevalence in four resource-limited settings.

Thorax

Gaviola C, Miele CH, Wise RA, Gilman RH, Jaganath D, Miranda JJ, Bernabe-Ortiz A, Hansel NN, Checkley W

Urbanization and Daily Exposure to Biomass Fuel Smoke Both Contribute to Chronic Bronchitis Risk in a Population with Low Prevalence of Daily Tobacco Smoking.

COPD

Miele CH, Jaganath D, Miranda JJ, Bernabe-Ortiz A, Gilman RH, Johnson CM, Diette GB, Wise RA, Checkley W

Distribution and transmission of Mycobacterium tuberculosis complex lineages among children in peri-urban Kampala, Uganda.

BMC pediatrics

Wampande EM, Mupere E, Jaganath D, Nsereko M, Mayanja HK, Eisenach K, Boom WH, Gagneux S, Joloba ML

Prevalence of chronic obstructive pulmonary disease and variation in risk factors across four geographically diverse resource-limited settings in Peru.

Respiratory research

Jaganath D, Miranda JJ, Gilman RH, Wise RA, Diette GB, Miele CH, Bernabe-Ortiz A, Checkley W

The role of pre-primary classes on school-age cognition in rural Nepal.

The Journal of pediatrics

Jaganath D, Khatry SK, Murray-Kolb LE, LeClerq SC, Christian P

A review of the global burden, novel diagnostics, therapeutics, and vaccine targets for cryptosporidium.

The Lancet. Infectious diseases

Checkley W, White AC, Jaganath D, Arrowood MJ, Chalmers RM, Chen XM, Fayer R, Griffiths JK, Guerrant RL, Hedstrom L, Huston CD, Kotloff KL, Kang G, Mead JR, Miller M, Petri WA, Priest JW, Roos DS, Striepen B, Thompson RC, Ward HD, Van Voorhis WA, Xiao L, Zhu G, Houpt ER

Global health research in narrative: a qualitative look at the FICRS-F experience.

The American journal of tropical medicine and hygiene

Bearnot B, Coria A, Barnett BS, Clark EH, Gartland MG, Jaganath D, Mendenhall E, Seu L, Worjoloh AG, Carothers CL, Vermund SH, Heimburger DC

Project HOPE: online social network changes in an HIV prevention randomized controlled trial for African American and Latino men who have sex with men.

American journal of public health

Young SD, Holloway I, Jaganath D, Rice E, Westmoreland D, Coates T

First detected Helicobacter pylori infection in infancy modifies the association between diarrheal disease and childhood growth in Peru.

Helicobacter

Jaganath D, Saito M, Gilman RH, Queiroz DM, Rocha GA, Cama V, Cabrera L, Kelleher D, Windle HJ, Crabtree JE, Checkley W

HIV-associated anemia after 96 weeks on therapy: determinants across age ranges in Uganda and Zimbabwe.

AIDS research and human retroviruses

Jaganath D, Walker AS, Ssali F, Musiime V, Kiweewa F, Kityo C, Salata R, Mugyenyi P

Contact investigation for active tuberculosis among child contacts in Uganda.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Jaganath D, Zalwango S, Okware B, Nsereko M, Kisingo H, Malone L, Lancioni C, Okwera A, Joloba M, Mayanja-Kizza H, Boom WH, Stein C, Mupere E

This is My Story: participatory performance for HIV and AIDS education at the University of Malawi.

Health education research

Jaganath D, Mulenga C, Hoffman RM, Hamilton J, Boneh G

Social networking technologies as an emerging tool for HIV prevention: a cluster randomized trial.

Annals of internal medicine

Young SD, Cumberland WG, Lee SJ, Jaganath D, Szekeres G, Coates T

Feasibility of recruiting peer educators for an online social networking-based health intervention.

Health education journal

Young SD, Harrell L, Jaganath D, Cohen AC, Shoptaw S

Childhood tuberculosis and malnutrition.

The Journal of infectious diseases

Jaganath D, Mupere E

Genomic analysis of sleep deprivation reveals translational regulation in the hippocampus.

Physiological genomics

Vecsey CG, Peixoto L, Choi JH, Wimmer M, Jaganath D, Hernandez PJ, Blackwell J, Meda K, Park AJ, Hannenhalli S, Abel T

Sleep deprivation impairs cAMP signalling in the hippocampus.

Nature

Vecsey CG, Baillie GS, Jaganath D, Havekes R, Daniels A, Wimmer M, Huang T, Brown KM, Li XY, Descalzi G, Kim SS, Chen T, Shang YZ, Zhuo M, Houslay MD, Abel T