Paul Ogongo, PhD

Asst Professional Researcher
Medicine
[email protected]
+1 628 206-8101

UCSF Center for Tuberculosis Initiatives:
UC TRAC TB RAMP Scholar | Class 2025
Mentored Scientist in TB Pilot Award | 2024
World TB Day Planning Committee 2023-24
UCSF DEIAB Committee Member

Publications: 

Application of microphysiological systems to unravel the mechanisms of schistosomiasis egg extravasation.

Frontiers in cellular and infection microbiology

Martin Omondi Alfred, Lucy Ochola, Kennedy Okeyo, Euiwon Bae, Paul Ogongo, David Odongo, Kariuki Njaanake, J. Paul Robinson

B cell heterogeneity in human tuberculosis highlights compartment-specific phenotype and functional roles.

Communications biology

Krause R, Ogongo P, Tezera L, Ahmed M, Mbano I, Chambers M, Ngoepe A, Magnoumba M, Muema D, Karim F, Khan K, Lumamba K, Nargan K, Madansein R, Steyn A, Shalek AK, Elkington P, Leslie A

High-parameter phenotypic characterization reveals a subset of human Th17 cells that preferentially produce IL-17 against M. tuberculosis antigen.

Frontiers in immunology

Ogongo P, Tran A, Marzan F, Gingrich D, Krone M, Aweeka F, Lindestam Arlehamn CS, Martin JN, Deeks SG, Hunt PW, Ernst JD

Rare Variable M. tuberculosis Antigens induce predominant Th17 responses in human infection.

bioRxiv : the preprint server for biology

Ogongo P, Wassie L, Tran A, Columbus D, Sharling L, Ouma G, Ouma SG, Bobosha K, Lindestam Arlehamn CS, Gandhi NR, Auld SC, Rengarajan J, Day CL, Altman JD, Blumberg HM, Ernst JD, TBRU ASTRa Study Group

Recognition and control of Mycobacterium tuberculosis-infected cells: from basics to the clinic: a NIAID/WGNV workshop report 2023

Recognition and control of Mycobacterium tuberculosis-infected cells: from basics to the clinic: a NIAID/WGNV workshop report 2023

Carly C Young, Mbali N. Mkhonza, Paul Ogongo

Do vaginal microbicides reduce the risk of HIV acquisition in women?

The Pan African medical journal

Obiero JA, Ogongo P, Mwethera PG, Wiysonge CS

Acquired Clinical Immunity to Malaria in Nonhuman Primates Coinfected with Schistosoma and Plasmodium Parasites.

Infection and immunity

Nyakundi RK, Hau J, Ogongo P, Nyamongo O, Jeneby M, Akinyi M, Mulei I, Nyundo F, Farah I, Malhotra I, Ozwara H, King CL, Kariuki T

Repeated Plasmodium falciparum infection in humans drives the clonal expansion of an adaptive γδ T cell repertoire.

Science translational medicine

von Borstel A, Chevour P, Arsovski D, Krol JMM, Howson LJ, Berry AA, Day CL, Ogongo P, Ernst JD, Nomicos EYH, Boddey JA, Giles EM, Rossjohn J, Traore B, Lyke KE, Williamson KC, Crompton PD, Davey MS

A Framework to Identify Antigen-Expanded T Cell Receptor Clusters Within Complex Repertoires.

Frontiers in immunology

Ceglia V, Kelley EJ, Boyle AS, Zurawski S, Mead HL, Harms CE, Blanck JP, Flamar AL, Kirschman JH, Ogongo P, Ernst JD, Levy Y, Zurawski G, Altin JA

Performance Evaluation of Lateral Flow Assays for Coronavirus Disease-19 Serology.

Clinics in laboratory medicine

Ochola L, Ogongo P, Mungai S, Gitaka J, Suliman S

Tissue-resident-like CD4+ T cells secreting IL-17 control Mycobacterium tuberculosis in the human lung.

The Journal of clinical investigation

Ogongo P, Tezera LB, Ardain A, Nhamoyebonde S, Ramsuran D, Singh A, Ng'oepe A, Karim F, Naidoo T, Khan K, Dullabh KJ, Fehlings M, Lee BH, Nardin A, Lindestam Arlehamn CS, Sette A, Behar SM, Steyn AJ, Madansein R, Kløverpris HN, Elkington PT, Leslie A

Topical microbicides for preventing sexually transmitted infections.

The Cochrane database of systematic reviews

Obiero J, Ogongo P, Mwethera PG, Wiysonge CS

Unbiased Profiling Reveals Compartmentalization of Unconventional T-Cells Within the Intestinal Mucosa Irrespective of HIV Infection.

Frontiers in immunology

Magnoumba M, Singh A, Ogongo P, Roider J, Asowata O, Fehlings M, Karim F, Ndung'u T, Anderson F, Leslie A, Kløverpris H

Single cell transcriptomics of the T cell response to Mycobacterium Tuberculosis reveals phenotypic diversity within and between infected individuals

Single cell transcriptomics of the T cell response to Mycobacterium Tuberculosis reveals phenotypic diversity within and between infected individuals

Junghwa Choi Kirschman; Paul Ogongo; Joel Ernst; John Altin

Anti-PD-1 immunotherapy leads to tuberculosis reactivation via dysregulation of TNF-α.

eLife

Tezera LB, Bielecka MK, Ogongo P, Walker NF, Ellis M, Garay-Baquero DJ, Thomas K, Reichmann MT, Johnston DA, Wilkinson KA, Ahmed M, Jogai S, Jayasinghe SN, Wilkinson RJ, Mansour S, Thomas GJ, Ottensmeier CH, Leslie A, Elkington PT

Differential skewing of donor-unrestricted and γδ T cell repertoires in tuberculosis-infected human lungs.

The Journal of clinical investigation

Ogongo P, Steyn AJ, Karim F, Dullabh KJ, Awala I, Madansein R, Leslie A, Behar SM

Publisher Correction: Group 3 innate lymphoid cells mediate early protective immunity against tuberculosis.

Nature

Ardain A, Domingo-Gonzalez R, Das S, Kazer SW, Howard NC, Singh A, Ahmed M, Nhamoyebonde S, Rangel-Moreno J, Ogongo P, Lu L, Ramsuran D, de la Luz Garcia-Hernandez M, Ulland TK, Darby M, Park E, Karim F, Melocchi L, Madansein R, Dullabh KJ, Dunlap M, Marin-Agudelo N, Ebihara T, Ndung'u T, Kaushal D, Pym AS, Kolls JK, Steyn A, Zúñiga J, Horsnell W, Yokoyama WM, Shalek AK, Kløverpris HN, Colonna M, Leslie A, Khader SA

Plasma IL-5 but Not CXCL13 Correlates With Neutralization Breadth in HIV-Infected Children.

Frontiers in immunology

Roider J, Porterfield JZ, Ogongo P, Muenchhoff M, Adland E, Groll A, Morris L, Moore PL, Ndung'u T, Kløverpris H, Goulder PJR, Leslie A

Group 3 innate lymphoid cells mediate early protective immunity against tuberculosis.

Nature

Ardain A, Domingo-Gonzalez R, Das S, Kazer SW, Howard NC, Singh A, Ahmed M, Nhamoyebonde S, Rangel-Moreno J, Ogongo P, Lu L, Ramsuran D, de la Luz Garcia-Hernandez M, K Ulland T, Darby M, Park E, Karim F, Melocchi L, Madansein R, Dullabh KJ, Dunlap M, Marin-Agudelo N, Ebihara T, Ndung'u T, Kaushal D, Pym AS, Kolls JK, Steyn A, Zúñiga J, Horsnell W, Yokoyama WM, Shalek AK, Kløverpris HN, Colonna M, Leslie A, Khader SA

Lung Tissue Resident Memory T-Cells in the Immune Response to Mycobacterium tuberculosis.

Frontiers in immunology

Ogongo P, Porterfield JZ, Leslie A

Major TCR Repertoire Perturbation by Immunodominant HLA-B*44:03-Restricted CMV-Specific T Cells.

Frontiers in immunology

Attaf M, Malik A, Severinsen MC, Roider J, Ogongo P, Buus S, Ndung'u T, Leslie A, Kløverpris HN, Matthews PC, Sewell AK, Goulder P

Nifuratel‐Nystatin combination for the treatment of mixed infections of bacterial vaginosis, vulvovaginal candidiasis, and trichomonal vaginitis

Cochrane Database Systematic Reviews

Jael Obrero, Stephen Rulisa, Paul Ogongo and Charles S Wiysonge

Protective Potential of Antioxidant Enzymes as Vaccines for Schistosomiasis in a Non-Human Primate Model.

Frontiers in immunology

Carvalho-Queiroz C, Nyakundi R, Ogongo P, Rikoi H, Egilmez NK, Farah IO, Kariuki TM, LoVerde PT

International Journal of Infectious Diseases

Identification and evaluation of Schistosoma mansoni proteins as diagnostic targets for schistosomiasis

Paul Ogongo