Science translational medicine

Pharmacokinetics of rifapentine and rifampin in a rabbit model of tuberculosis and correlation with clinical trial data.

Science translational medicine

Rifat D, Prideaux B, Savic RM, Urbanowski ME, Parsons TL, Luna B, Marzinke MA, Ordonez AA, DeMarco VP, Jain SK, Dartois V, Bishai WR, Dooley KE

Exposure to SIV in utero results in reduced viral loads and altered responsiveness to postnatal challenge.

Science translational medicine

Baker CA, Swainson L, Lin DL, Wong S, Hartigan-O'Connor DJ, Lifson JD, Tarantal AF, McCune JM

Dysbiosis of the gut microbiota is associated with HIV disease progression and tryptophan catabolism.

Science translational medicine

Vujkovic-Cvijin I, Dunham RM, Iwai S, Maher MC, Albright RG, Broadhurst MJ, Hernandez RD, Lederman MM, Huang Y, Somsouk M, Deeks SG, Hunt PW, Lynch SV, McCune JM

SIV replication in the infected rhesus macaque is limited by the size of the preexisting TH17 cell compartment.

Science translational medicine

Hartigan-O'Connor DJ, Abel K, Van Rompay KK, Kanwar B, McCune JM

Breaking free of sample size dogma to perform innovative translational research.

Science translational medicine

Bacchetti P, Deeks SG, McCune JM

IL-22+ CD4+ T cells are associated with therapeutic trichuris trichiura infection in an ulcerative colitis patient.

Science translational medicine

Broadhurst MJ, Leung JM, Kashyap V, McCune JM, Mahadevan U, McKerrow JH, Loke P

Tryptophan catabolism by indoleamine 2,3-dioxygenase 1 alters the balance of TH17 to regulatory T cells in HIV disease.

Science translational medicine

Favre D, Mold J, Hunt PW, Kanwar B, Loke P, Seu L, Barbour JD, Lowe MM, Jayawardene A, Aweeka F, Huang Y, Douek DC, Brenchley JM, Martin JN, Hecht FM, Deeks SG, McCune JM

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