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Christopher Berger, MD, MSIMT is an assistant professor in the UCSF Division of Pulmonary Critical Care Medicine, clinically based at Zuckerberg San Francisco General Hospital. His research focuses on improving tuberculosis screening, diagnosis, and treatment programs globally through the use of implementation science and human-centered design principles. He works with Dr.
My research is focused on the innate immune mechanisms that control M. tuberculosis infection. Autophagy is one mechanism that macrophages use to control microbial infection by targeting bacteria for degradation in the lysosome.
My research group focuses on the 1) Development and evaluation of TB diagnostics and 2) Implementation and dissemination of evidence-based interventions to improve TB care in high burden countries. I helped establish a TB/HIV cohort at Mulago Hospital in Kampala, Uganda. The cohort has resulted in important publications related to the etiology and outcomes of pneumonia and the performance of TB diagnostics in this population. Also in Uganda, I helped establish the Uganda Tuberculosis Implementation Research Consortium (U-TIRC).