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Matthew Murrill is an Assistant Professor of Hospital Medicine and an epidemiologist. His overarching research goal is to improve tuberculosis (TB) care, particularly TB prevention, by leveraging epidemiologic and implementation science methods.
UCSF Center for Tuberculosis Initiatives:
UC TRAC TB RAMP Scholar | Class 2025
Mentored Scientist in TB Pilot Award | 2024
World TB Day Planning Committee 2023-24
UCSF DEIAB Committee Member
Co-Director, UC TRAC Clinical & Population Health Science Core
Medicine
The objective of my research is to design, implement, and optimize clinical trials for new treatments for drug-sensitive and drug-resistant tuberculosis in order to deliver safer and more efficacious regimens for patients. A key focus of my research has been to improve the design of TB clinical trials so that regimen development is faster and more efficient. This was motivated by my PhD thesis evaluating surrogate endpoints for TB trials, and has grown in a number of areas through the various collaborations and consortia that I contribute to.
My tuberculosis-related research focuses on the intersections of alcohol, HIV, and TB in sub-Saharan Africa. My current work is seeking to establish associations between alcohol use levels and tuberculosis infection incidence and prevalence among people living with HIV in order to inform TB prevention efforts. Clinically, I attend on the HIV/Infectious disease inpatient consult service at ZSFG and care for patients at the Ward 86 Positive Health Practice.
Mike currently serves as the Chief Science Officer for PEPFAR in the Bureau of Global Health Security and Diplomacy in the US State Department. He also serves as Associate Director of the Center for Global Health Diplomacy, Delivery and Economics. He is an HIV clinician and sees patients at San Francisco General Hospital.
My research interests are the epidemiology and prevention of infectious and tropical diseases of public health importance, both internationally and domestically, with a primary focus on HIV and AIDS. My work is funded primarily by the Centers for Disease Control and Prevention through the Presidential Emergency Plan for AIDS Relief. I also have smaller projects dealing with the epidemiology of tuberculosis in California, the prevention of childhood injury, immunizations and bioterrorism. I am a member of the AIDS Research Institute's Executive Committee.